Table 2. Carbon monoxide calibration data showing peak areas measured (labeled uncorrected data) versus actual and predicted concentrations from the 1st order regression
analysis, and the error associated with each data point using a different calibration test
software package.
Calibration Protocol
1) Determine the gas (or gases)
of interest
2) Predict interferences (if any)
3) Determine concentration range(s)
of interest
4) Determine resolution required
5) Acquire spectral calibration data
6) Determine best fit for data
7) Determine accuracy of method
8) Validate method with check
standards
9) Determine calibration/validation
intervals
Conclusions
In Part 1 of these three articles we defined the theoretical methods
and backgrounds for FTIR absorbances and the requirements of an
effective FTIR gas analytical system. In Part 2 we defined the physical
instrumental and control requirements used to design and implement a fully functional F TIR gas analytical system. In Part 3 we have
shown the nuances and understanding required for an accurate
reduction of data and the validation of results. (See sidebar for the
protocol considerations for generation and validation of an effective
calibration method.)
G&I
KIP VAUGHAN IS CURRENTLY IN
HIS SENIOR YEAR AT DURHAM ACADEMY
IN DURHAM, NOR TH CAROLINA. HE HAS
WORKED FOR HIS FATHER AT CUSTOM
GAS SOLUTIONS AS A SUMMER INTERN
FOR THREE YEARS AND PLANS TO PURSUE
A CAREER IN THE SCIENCES. HE ASSISTED
WITH RESEARCH AND GRAPHICS
.
Acknowledgements:
We appreciate the assistance of the following companies and/or
persons who contributed graphics, data, or information to this
current article:
Thermo Fisher Scientific, 5225 Verona Road, Madison, WI, 53711.
Contact: Ken Gowin at ken.gowin@thermofisher.com.
1. S.O. Vaughan, W.K.Vaughan. “FTIR Gas Analytical Systems Design and Utilization Considerations,” Gases & Instrumentation,
Vol. 2, Issue 6, (November/December 2008) pp. 14-17.
2. S.O. Vaughan, W.K.Vaughan. “FTIR Gas Analytical Systems Design
and Utilization Considerations,” Gases & Instrumentation, Vol. 3,
Issue 1, (January/February 2009) pp. 16-22.
DR. STEPHEN VAUGHAN IS THE
FOUNDER AND PRESIDENT AND COO OF
CUSTOM GAS SOLUTIONS, LLC, 1750 EAST
CLUB BOULEVARD, DURHAM, NC 27704.
DR. VAUGHAN IS A LEADING AUTHORITY IN THE
FOURIER TRANSFORM INFRAREDSPECTROSCOPIC
(FTIR) ANALYSIS OF GASES AND IN THE
DEVELOPMENT AND IMPLEMENTATION OF GAS
MIXING AND DELIVERY SYSTEMS FOR BOTH
PROCESS AND ANALYTICAL USE. DR. VAUGHAN
HOLDS A B.S. DEGREE IN CHEMISTRY FROM
THE UNIVERSITY OF NORTH CAROLINA, CHAPEL HILL, NORTH CAROLINA, AND AN M.A.
AND PH.D. IN PHYSICAL CHEMISTRY FROM THE JOHNS HOPKINS UNIVERSITY, BALTIMORE,
MARYLAND. HE CAN BE REACHED AT 919-220-2570 OR STEVE@CUSTOMGAS.COM
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